Extracorporeally irradiated autograft-prosthetic composite arthroplasty using AML extensively porous-coated stem for proximal femur reconstruction: a clinical analysis of 14 patients

J Surg Oncol. 2009 Oct 1;100(5):418-22. doi: 10.1002/jso.21351.

Abstract

Background and objectives: Allograft-prosthetic composite for reconstruction of the proximal femur after tumor excision is widely used as an alternative to megaprosthesis. To achieve greater biological fixation, we employed a long-stem prosthesis that is cemented proximally into the extracorporeally irradiated autograft and press-fit distally into the host femur without any supplementary plate fixation of the junction instead of the standard all-cemented technique.

Methods: From 1997 to 2002, 14 patients underwent proximal femur reconstruction with extracorporeally irradiated autograft-prosthetic composite using an AML extensively porous-coated long stem for reconstruction of the bone defect of tumor excisions.

Results: At the mean follow-up period of 65.7 months, only one patient (8.1%) developed non-union and another died of disease before union of the junction. The remaining 12 patients (85%) achieved union at a mean of 20.3 weeks (range, 14-40 weeks) without major complication. The mean functional Enneking score was 72.1% (range, 53-93%).

Conclusions: These clinical results show that this reliable and satisfactory technique promotes union through compression at the host-graft junction with weight-bearing by leaving the distal portion of the femoral stem uncemented into the host bone.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Arthroplasty, Replacement, Hip / methods*
  • Child
  • Coated Materials, Biocompatible*
  • Female
  • Femoral Neoplasms / surgery*
  • Femur / radiation effects*
  • Hip Prosthesis*
  • Humans
  • Limb Salvage / methods
  • Lymphoma / surgery
  • Male
  • Middle Aged
  • Prosthesis Design
  • Sarcoma / surgery
  • Thymoma / surgery
  • Transplantation, Autologous
  • Weight-Bearing

Substances

  • Coated Materials, Biocompatible