Cribrarione C, a naphthoquinone pigment from the myxomycete Cribraria meylanii

Chem Pharm Bull (Tokyo). 2009 Aug;57(8):894-5. doi: 10.1248/cpb.57.894.

Abstract

Chemical investigation of field-collected fruit bodies of the myxomycete Cribraria meylanii resulted in the isolation of a naphthoquinone pigment, cribrarione C, and its structure was elucidated by spectral data as 2,5,6,7-tetrahydroxy-1,4-naphthoquinone (1). This compound (1) had been synthesized previously, while it was isolated here for the first time as a natural product, and its NMR and MS data are described in this study.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Dose-Response Relationship, Drug
  • Fruiting Bodies, Fungal / chemistry
  • HeLa Cells
  • Humans
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Myxomycetes / chemistry*
  • Naphthoquinones / chemistry*
  • Naphthoquinones / isolation & purification*
  • Naphthoquinones / pharmacology
  • Pigments, Biological / chemistry*
  • Pigments, Biological / isolation & purification*
  • Pigments, Biological / pharmacology
  • Reference Standards
  • Staphylococcus aureus / drug effects
  • Structure-Activity Relationship

Substances

  • 2,5,6,7-tetrahydroxy-1,4-naphthoquinone
  • Naphthoquinones
  • Pigments, Biological