Smoking cessation in patients with mental disorders Smoking prevalence is higher in all mental disorders, particularly depression and schizophrenia, through complex and multifactorial associations. Among patients with mental disorders, smoking cessation increases risk of relapse and recurring depression and might decrease smoking abstinence. Though smoking cessation interventions are less effective, professional support, relapse prevention strategies, nicotine replacement and bupropion help some patients to quit smoking. New strategies should overcome barriers to smoking cessation in psychiatric settings and improve intervention with smokers. Research needs to further explore the link between smoking and mental health and develop effective interventions integrated in psychiatric care provided to smokers.