[Chyluria presenting as milky urine and nephrotic-range proteinuria and milky urine: chyluria or glomerulopathy? Case report and literature review]

Nephrol Ther. 2009 Dec;5(7):642-7. doi: 10.1016/j.nephro.2009.06.003. Epub 2009 Jul 23.
[Article in French]

Abstract

A patient is admitted in hospital to explore a nephrotic proteinuria associated with milky urine. This is explained by a chyluria (presence of lymphatic fluid in the urines), which is due to a pyelolymphatic fistula probably linked to a lymphatic filariasis. Usually, the diagnosis of chyluria can be confirmed by the presence of urinary chylomicrons. The presence of an urinary-lymphatic fistula can be proved by different techniques (cystoscopy, retrograde pyelography, uroscanner, lymphoscintigraphy). The main cause of chyluria is parasitic infections (filarial infection, echinococcus, cysticercosis), but other causes can be found, such as granulomatosis, neoplasia, lymphatic malformations, or sequela of surgery or traumatism. Chyluria is one of the causes of post-nephronic nephrotic proteinuria. Depending on the impact of the chyluria for the patient, there will either be no treatment, or a treatment by sclerotherapy or surgery.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Chyle*
  • Humans
  • Kidney Diseases / complications*
  • Male
  • Middle Aged
  • Proteinuria / etiology*
  • Urine