[Glucagon perfusion in paraneoplastic hypoglycemia]

Endocrinol Nutr. 2009 Mar;56(3):143-6. doi: 10.1016/S1575-0922(09)70846-0. Epub 2009 May 18.
[Article in Spanish]

Abstract

Hypoglycemia is a common emergency, and is usually due to insulin therapy or oral hypoglycemic treatment in diabetic patients. In some cases, hypoglycemia can be a paraneoplastic sign. We report the case of a 61-year-old woman with a malignant peritoneal mesothelioma, who was admitted to hospital because of diminished consciousness. The final diagnosis was paraneoplastic hypoglycemia with a positive response to glucagon. The patient was finally discharged with glucagon perfusion.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Coma / etiology
  • Fatal Outcome
  • Female
  • Glucagon / administration & dosage
  • Glucagon / therapeutic use*
  • Humans
  • Hypoglycemia / drug therapy*
  • Hypoglycemia / etiology
  • Infusions, Intravenous
  • Insulin-Like Growth Factor II / metabolism
  • Mesothelioma / complications
  • Mesothelioma / drug therapy
  • Mesothelioma / metabolism
  • Middle Aged
  • Models, Biological
  • Palliative Care
  • Paraneoplastic Syndromes / drug therapy*
  • Paraneoplastic Syndromes / etiology
  • Perfusion
  • Peritoneal Neoplasms / complications
  • Peritoneal Neoplasms / drug therapy
  • Peritoneal Neoplasms / metabolism
  • Protein Precursors / metabolism
  • Recurrence

Substances

  • Antineoplastic Agents
  • Protein Precursors
  • proinsulin-like growth factor II
  • Insulin-Like Growth Factor II
  • Glucagon