Hepatic angiomyolipoma: dynamic computed tomography features and clinical correlation

World J Gastroenterol. 2009 Jul 21;15(27):3417-20. doi: 10.3748/wjg.15.3417.

Abstract

Aim: To study the dynamic computed tomography (CT) features of hepatic angiomyolipoma (AML) in patients with or without tuberous sclerosis complex (TSC).

Methods: The clinical information, CT findings and histopathological results of hepatic AML were analyzed retrospectively in 10 patients.

Results: Hepatic AML was prone to occur in female patients (7/10), and most of the patients (8/10) had no specific symptoms. All tumors presented as well-defined, unenveloped nodules in the liver. Six patients with sporadic hepatic AML had a solitary hepatic nodule with a definite fat component. Non-fat components of the hepatic lesions were enhanced earlier and persistently. Prominent central vessels were noted in the portal venous phase in three patients. In four patients with hepatic AML and TSC, most of the nodules were within the peripheral liver. Seven fat-deficient nodules were found with earlier contrast enhancement and rapid contrast material washout in two patients. Lymphangioleiomyomatosis was found in one patient.

Conclusion: Imaging features of hepatic AML are characteristic. Correct diagnosis preoperatively can be made in combination with clinical features.

MeSH terms

  • Adult
  • Aged
  • Angiomyolipoma* / diagnosis
  • Angiomyolipoma* / diagnostic imaging
  • Angiomyolipoma* / pathology
  • Female
  • Humans
  • Liver Neoplasms* / diagnosis
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / pathology
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed / methods*
  • Tuberous Sclerosis* / diagnosis
  • Tuberous Sclerosis* / diagnostic imaging
  • Tuberous Sclerosis* / pathology
  • Young Adult