Endothelial keratoplasty: the use of viscoelastic as an aid in reattaching the dislocated graft in abnormally structured eyes

Ophthalmology. 2009 Oct;116(10):1897-900. doi: 10.1016/j.ophtha.2009.03.049. Epub 2009 Jul 9.

Abstract

Purpose: To explore the feasibility of reattaching the dislocated graft with viscoelastic in abnormally structured eyes after Descemet-stripping automated endothelial keratoplasty (DSAEK).

Design: Retrospective case series.

Participants: Five pseudophakic bullous keratopathy cases (5 eyes) with a history of vitrectomy and/or iris-lens diaphragm injury.

Methods: After DSAEK, graft dislocation occurred in each of the 5 cases (5 eyes). We attempted to fill the anterior chamber (AC) with an air bubble to push up the dislocated graft, but this was not successful. We then injected balanced salt solution into the vitreous body to obtain normal intraocular pressure (IOP) and injected a small amount of viscoelastic (Healon GV) to support the AC. Next, we injected an air bubble into the AC.

Main outcome measures: The position of the grafts was checked with a slit lamp and anterior segment optical coherence tomography (AS-OCT). The IOP was observed with Goldmann tonometer. The best visual acuity was checked.

Results: As observed through the slit lamp and AS-OCT, the grafts reattached well in all patients. The IOP was normal in all patients except one, who had high IOP 1 month postoperatively. After receiving drug treatment, the patient's IOP returned to normal. The grafts had slight edema on postoperative day 1, but became transparent between days 5 and 8.

Conclusions: Viscoelastic aided in the reattachment of the dislocated graft in eyes with a history of vitrectomy and/or iris-lens diaphragm injury. The presence of viscoelastic in the AC in the early period of post-DSAEK was well tolerated in this small series.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anterior Chamber / drug effects
  • Anterior Chamber / pathology
  • Corneal Diseases / diagnosis
  • Corneal Diseases / surgery*
  • Corneal Transplantation / methods*
  • Descemet Membrane / surgery
  • Endothelium, Corneal / pathology
  • Endothelium, Corneal / transplantation*
  • Humans
  • Hyaluronic Acid / therapeutic use*
  • Intraocular Pressure / physiology
  • Middle Aged
  • Reoperation
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Tonometry, Ocular
  • Viscosupplements / therapeutic use*
  • Visual Acuity / physiology
  • Young Adult

Substances

  • Viscosupplements
  • Hyaluronic Acid