Abstract
Recurring adult-type granulosa cell tumors of the ovary are usually treated by surgical resection followed by chemotherapy or radiation. However, the results of such treatment are disappointing. We describe 4 patients in whom recurrent ovarian granulosa cell tumors were treated with an aromatase inhibitor, with promising results.
MeSH terms
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Adult
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Aged
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Anastrozole
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Aromatase Inhibitors / therapeutic use*
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Female
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Granulosa Cell Tumor / drug therapy*
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Granulosa Cell Tumor / pathology
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Granulosa Cell Tumor / surgery
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Humans
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Letrozole
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Middle Aged
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Neoplasm Recurrence, Local / drug therapy*
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Neoplasm Recurrence, Local / pathology
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Neoplasm Recurrence, Local / surgery
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Nitriles / therapeutic use*
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Ovarian Neoplasms / drug therapy*
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Ovarian Neoplasms / pathology
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Ovarian Neoplasms / surgery
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Ovariectomy
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Prognosis
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Treatment Outcome
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Triazoles / therapeutic use*
Substances
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Aromatase Inhibitors
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Nitriles
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Triazoles
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Anastrozole
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Letrozole