Basic science review. Vascular distensibility as a predictive tool in the management of small asymptomatic abdominal aortic aneurysms

Vasc Endovascular Surg. 2009 Aug-Sep;43(4):333-8. doi: 10.1177/1538574409336019. Epub 2009 Jun 24.

Abstract

Background: This study investigates whether baseline aortic wall distensibility serves as a supplemental bio-marker for AAA progression and need for later repair.

Methods: In 1998, 61 males with a small asymptomatic AAAs had a baseline measurement of elasticity and stiffness, using an echo-tracking ultrasound system (Diamove). The cohort was followed till 2005 concerning Dmax, expansion rate, operations for AAA, hospitalisation do to cardiovascular disease and death.

Results: During follow-up, 49% died, and 45.9% were hospitalised do to cardiovascular disease, compared to Dmax, Ep and b no significant associations were found. Elasticity correlated moderately to annual expansion rate and Dmax. Good correlation was found between annual expansion rate and Dmax. ROC-curve analysis showed that elasticity, stiffness and Dmax all tended to predict future need for AAA-repair.

Conclusion: Baseline aortic wall distensibility may provide an additional parameter for AAA to optimize the indication and time for elective repair.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aorta, Abdominal / diagnostic imaging
  • Aorta, Abdominal / physiopathology
  • Aorta, Abdominal / surgery
  • Aortic Aneurysm, Abdominal / complications
  • Aortic Aneurysm, Abdominal / diagnosis*
  • Aortic Aneurysm, Abdominal / mortality
  • Aortic Aneurysm, Abdominal / physiopathology
  • Aortic Aneurysm, Abdominal / surgery
  • Blood Pressure
  • Cardiovascular Diseases / etiology
  • Denmark / epidemiology
  • Disease Progression
  • Elasticity
  • Hospitalization
  • Humans
  • Male
  • Mass Screening / methods*
  • Predictive Value of Tests
  • Prospective Studies
  • ROC Curve
  • Time Factors
  • Ultrasonography
  • Vascular Surgical Procedures