Adenovirus type 3 outbreak in connecticut associated with a novel variant

J Med Virol. 2009 Aug;81(8):1380-4. doi: 10.1002/jmv.21539.

Abstract

An adenovirus outbreak occurred in New Haven, Connecticut in 2006-2007. Molecular typing revealed a twofold increase in adenovirus type 3 infections. Restriction enzyme analysis (REA) indicated that the CT outbreak was largely due to a marked increase in the novel Ad3a51 strain. This outbreak represents the first detection of Ad3a51 in the United States. While most infections were mild, children under 3 were at increased risk for severe disease and one patient with underlying disease died.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adenoviridae Infections / epidemiology*
  • Adenoviridae Infections / virology*
  • Adenoviruses, Human / classification*
  • Adenoviruses, Human / genetics
  • Adenoviruses, Human / isolation & purification*
  • Child
  • Child, Preschool
  • Connecticut / epidemiology
  • DNA Fingerprinting
  • DNA, Viral / genetics
  • Disease Outbreaks*
  • Female
  • Humans
  • Male
  • Molecular Epidemiology
  • Polymorphism, Restriction Fragment Length
  • Prohibitins

Substances

  • DNA, Viral
  • PHB2 protein, human
  • Prohibitins