Abstract
Dengue viruses are the most important arboviruses causing human disease. Expansion of the disease in recent decades to include more geographical areas of the world, an appreciation of the disease burden and market potentials have spurred a flurry of activity in the development of vaccines to combat dengue viruses. Recent progress in this area and some of the obstacles associated with this development are discussed.
MeSH terms
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Animals
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Clinical Trials as Topic
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Dengue / immunology*
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Dengue / prevention & control*
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Dengue Vaccines / administration & dosage
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Dengue Vaccines / immunology*
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Dengue Virus / genetics
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Dengue Virus / immunology*
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Humans
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Tropical Medicine / trends*
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Vaccination*
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Vaccines, DNA / administration & dosage
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Vaccines, DNA / immunology
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Vaccines, Subunit / administration & dosage
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Vaccines, Subunit / immunology
Substances
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Dengue Vaccines
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Vaccines, DNA
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Vaccines, Subunit