Catalytic microcapsules assembled from enzyme-nanoparticle conjugates at oil-water interfaces

Angew Chem Int Ed Engl. 2009;48(29):5341-4. doi: 10.1002/anie.200901590.

Abstract

Involuntary association: Anionic beta-galactosidase enzymes associate with positively charged Au nanoparticles to produce reduced-charge conjugates, which assemble at oil-water interfaces to result in stable microcapsules (see picture). The microcapsules were formed quickly and showed high enzymatic activity, which makes them promising materials for biotechnology applications.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Capsules / chemistry*
  • Catalysis
  • Enzymes, Immobilized / chemistry*
  • Gold / chemistry*
  • Metal Nanoparticles / chemistry*
  • Metal Nanoparticles / ultrastructure
  • Oils / chemistry
  • Surface Properties
  • Water / chemistry
  • beta-Galactosidase / chemistry*
  • beta-Galactosidase / metabolism*

Substances

  • Capsules
  • Enzymes, Immobilized
  • Oils
  • Water
  • Gold
  • beta-Galactosidase