Abstract
The influence of polymorphisms in the CIITA and IL-6 genes on donor-specific human leucocyte antigen antibody production was investigated in a cohort of renal transplant recipients and their donors. CIITA and IL-6 single nucleotide polymorphisms were found to be associated with donor-specific human leucocyte antigen antibody production post-transplantation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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Genotype
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Graft Rejection / genetics
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Graft Rejection / immunology*
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Humans
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Interleukin-6 / genetics*
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Interleukin-6 / immunology
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Isoantibodies / biosynthesis*
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Isoantibodies / blood
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Kidney Transplantation / immunology*
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Nuclear Proteins / genetics*
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Nuclear Proteins / immunology
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Pilot Projects
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Polymorphism, Single Nucleotide / genetics
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Polymorphism, Single Nucleotide / immunology
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Tissue Donors
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Trans-Activators / genetics*
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Trans-Activators / immunology
Substances
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Interleukin-6
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Isoantibodies
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MHC class II transactivator protein
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Nuclear Proteins
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Trans-Activators