Abstract
Apoptosis appears to be a carefully orchestrated process for the ordered dismantling of cells. A recent paper in BMC Developmental Biology shows that the disassembly of adherens junctions during apoptosis in Drosophila is progressive and requires the amino-terminal cleavage of the beta-catenin Armadillo by the apoptotic effector caspase DrICE.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adherens Junctions / metabolism
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Animals
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Apoptosis*
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Armadillo Domain Proteins / metabolism
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Caspases / metabolism
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Cell Adhesion
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Drosophila Proteins / metabolism
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Drosophila melanogaster
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Epithelial Cells / physiology
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Transcription Factors / metabolism
Substances
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ARM protein, Drosophila
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Armadillo Domain Proteins
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Drosophila Proteins
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Transcription Factors
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Caspases
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drICE protein, Drosophila