Surgery of left ventricular aneurysm: a propensity score-matched study of outcomes following different repair techniques

Interact Cardiovasc Thorac Surg. 2009 Sep;9(3):431-6. doi: 10.1510/icvts.2009.207134. Epub 2009 Jun 10.

Abstract

To evaluate early and late outcomes of modified left ventricular reconstruction (VR) and linear repair (LR) of post-infarct left ventricular aneurysm (LVA). A total of 514 patients were consecutively operated on for LVA with modified VR technique in 145 and LR in 352 patients. Using the propensity score-matching method, we selected 202 patients (101 LRs vs. 101 VRs) with similar pre- and intra-operative characteristics and compared their clinical outcomes. After matching, the two groups of patients were similar with regard to baseline data. The increment of left ventricular ejection fraction (LVEF) in VR group was more significant than that in LR group. Operative mortality was 2.0% (2.0% LRs vs. 2.0% VRs, P=NS). There was a statistically significant difference between LR and VR patients in MACCEs (29.7% LRs vs. 13.9% VRs, P<0.01) and hospital readmissions (51.5% LRs vs. 30.7% VRs, P<0.01). Overall long-term mortality and cardiac mortality were the same between the two groups (mortality: 11.9% LRs vs. 11.9% VRs, P=NS; cardiac mortality: 9.9% LRs vs. 7.9% VRs, P=NS). The technique of repairing LVA did not affect the early and later mortality.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cardiac Surgical Procedures* / adverse effects
  • Cardiac Surgical Procedures* / mortality
  • Cerebrovascular Disorders / etiology
  • Databases as Topic
  • Female
  • Heart Aneurysm / etiology
  • Heart Aneurysm / mortality
  • Heart Aneurysm / physiopathology
  • Heart Aneurysm / surgery*
  • Heart Ventricles / surgery
  • Hospital Mortality
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Myocardial Infarction / complications*
  • Myocardial Infarction / mortality
  • Myocardial Infarction / physiopathology
  • Myocardial Infarction / surgery
  • Patient Readmission
  • Proportional Hazards Models
  • Recovery of Function
  • Risk Assessment
  • Stroke Volume
  • Time Factors
  • Treatment Outcome
  • Ventricular Function, Left