Production of nanoaerosols of sparingly water-soluble drugs: the effect of indomethacin nanoparticles

Dokl Biochem Biophys. 2009 Mar-Apr:425:106-9. doi: 10.1134/s1607672909020136.

Authors

A A Onishchuk¹, T G Tolstikova, I V Sorokina, A M Baklanov, V V Karasev, V V Boldyrev, V M Fomin

Affiliation

¹ Institute of Chemical Kinetics and Combustion, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia.

PMID: 19496334
DOI: 10.1134/s1607672909020136

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Administration, Inhalation
Aerosols
Animals
Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
Anti-Inflammatory Agents, Non-Steroidal / chemistry*
Anti-Inflammatory Agents, Non-Steroidal / metabolism
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Drug Stability
Edema / drug therapy
Edema / pathology
Indomethacin / administration & dosage*
Indomethacin / chemistry*
Indomethacin / metabolism
Indomethacin / therapeutic use
Lung / metabolism
Male
Mice
Nanoparticles*
Particle Size
Solubility
Temperature
Volatilization
Water / chemistry*

Substances

Aerosols
Anti-Inflammatory Agents, Non-Steroidal
Water
Indomethacin