Abstract
A simple addition with a large impact: Addition of aromatic amines such as phenanthroline and 4-DMAP (4-dimethylaminopyridine) increases copper(I)-catalyzed azide alkyne cycloaddition (CuAAC) catalytic activity of [CuCl(SIMes)] at a large range of temperatures in such a way that efficient catalysis can safely take place in hydro-alcoholic solvents (see scheme).
MeSH terms
-
4-Aminopyridine / analogs & derivatives*
-
4-Aminopyridine / chemistry
-
Alcohols / chemistry
-
Alkynes / chemistry
-
Azides / chemistry
-
Catalysis
-
Copper / chemistry*
-
Molecular Structure
-
Nitrogen / chemistry*
-
Phenanthrolines / chemistry*
-
Solvents
-
Temperature
Substances
-
Alcohols
-
Alkynes
-
Azides
-
Phenanthrolines
-
Solvents
-
Copper
-
4-Aminopyridine
-
Nitrogen
-
4-dimethylaminopyridine