Nutlin kills cancer cells via mitochondrial p53

Cell Cycle. 2009 Jun 1;8(11):1647-8.
No abstract available

Publication types

  • News
  • Comment

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Apoptosis
  • Cell Line, Tumor
  • Humans
  • Imidazoles / pharmacology*
  • Mitochondria / metabolism*
  • Piperazines / pharmacology*
  • Proto-Oncogene Proteins c-mdm2 / antagonists & inhibitors
  • Proto-Oncogene Proteins c-mdm2 / metabolism
  • Tumor Suppressor Protein p53 / metabolism*
  • Ubiquitination

Substances

  • Antineoplastic Agents
  • Imidazoles
  • Piperazines
  • Tumor Suppressor Protein p53
  • nutlin 1
  • MDM2 protein, human
  • Proto-Oncogene Proteins c-mdm2