EEG-fMRI coregistration in non-ketotic hyperglycemic occipital seizures

Alessandra Del Felice; Tiziano Zanoni; Mirko Avesani; Emanuela Formaggio; Silvia Storti; Antonio Fiaschi; Giuseppe Moretto; Paolo Manganotti

doi:10.1016/j.eplepsyres.2009.03.025

EEG-fMRI coregistration in non-ketotic hyperglycemic occipital seizures

Epilepsy Res. 2009 Aug;85(2-3):321-4. doi: 10.1016/j.eplepsyres.2009.03.025. Epub 2009 May 14.

Authors

Alessandra Del Felice¹, Tiziano Zanoni, Mirko Avesani, Emanuela Formaggio, Silvia Storti, Antonio Fiaschi, Giuseppe Moretto, Paolo Manganotti

Affiliation

¹ Department of Neurological and Visual Science, University of Verona, Italy.

PMID: 19446439
DOI: 10.1016/j.eplepsyres.2009.03.025

Abstract

We report the first case, to our knowledge, of non-ketotic hyperglycemic (NKH) related occipital seizures studied by continuous EEG-fMRI in an undiagnosed diabetic patient. Ictal EEG showed left posterior spikes and sharp-waves. Seizures subsided after insulin therapy was started. Continuous EEG-fMRI was performed and BOLD activation was identified in the left Brodmann's area 18 (visual association area). Activation of an epileptic focus related with the patient's metabolic disturbance can be postulated.

Publication types

Case Reports

MeSH terms

Anticonvulsants / therapeutic use
Carbamazepine / therapeutic use
Electroencephalography
Female
Humans
Hyperglycemia / complications*
Hyperglycemia / drug therapy
Hypoglycemic Agents / therapeutic use
Image Processing, Computer-Assisted
Insulin / therapeutic use
Magnetic Resonance Imaging
Middle Aged
Occipital Lobe / pathology*
Occipital Lobe / physiopathology
Oxygen / blood
Seizures / complications*
Seizures / pathology*
Seizures / physiopathology
Tomography, Emission-Computed, Single-Photon

Substances

Anticonvulsants
Hypoglycemic Agents
Insulin
Carbamazepine
Oxygen