Prevalence and molecular diversity of hepatitis B virus and hepatitis delta virus in urban and rural populations in northern Gabon in central Africa

J Clin Microbiol. 2009 Jul;47(7):2265-8. doi: 10.1128/JCM.02012-08. Epub 2009 May 13.

Abstract

The prevalence of hepatitis B virus (HBV) surface antigen was significantly higher in urban (12.9%) than in rural (7.6%) populations (P = 0.003), but no difference was found in the prevalence of hepatitis delta virus (HDV), which was high in both populations. Phylogenetic analysis showed the circulation of HBV-A3 and -E genotypes and the presence of HDV-1, HDV-7, and HDV-8 clades.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Africa, Central / epidemiology
  • Aged
  • Aged, 80 and over
  • Cluster Analysis
  • Female
  • Gabon / epidemiology
  • Hepatitis B / epidemiology*
  • Hepatitis B / virology
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B virus / classification*
  • Hepatitis B virus / genetics*
  • Hepatitis B virus / isolation & purification
  • Hepatitis D / epidemiology*
  • Hepatitis D / virology
  • Hepatitis Delta Virus / classification*
  • Hepatitis Delta Virus / genetics*
  • Hepatitis Delta Virus / isolation & purification
  • Humans
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Phylogeny
  • Polymorphism, Genetic*
  • Prevalence
  • Rural Population
  • Sequence Analysis, DNA
  • Sequence Homology
  • Urban Population
  • Young Adult

Substances

  • Hepatitis B Surface Antigens

Associated data

  • GENBANK/FJ349266
  • GENBANK/FJ349267
  • GENBANK/FJ349268
  • GENBANK/FJ349269
  • GENBANK/FJ349270
  • GENBANK/FJ349271
  • GENBANK/FJ349272
  • GENBANK/FJ349273
  • GENBANK/FJ349274
  • GENBANK/FJ349275
  • GENBANK/FJ349276
  • GENBANK/FJ349277
  • GENBANK/FJ349279
  • GENBANK/FJ349280
  • GENBANK/FJ349281
  • GENBANK/FJ349282
  • GENBANK/FJ349283
  • GENBANK/FJ349284
  • GENBANK/FJ349285
  • GENBANK/FJ349286
  • GENBANK/FJ349287
  • GENBANK/FJ349288
  • GENBANK/FJ349289
  • GENBANK/FJ349290
  • GENBANK/FJ349291
  • GENBANK/FJ349292
  • GENBANK/FJ349293
  • GENBANK/FJ349294
  • GENBANK/FJ349295
  • GENBANK/FJ349296