A highly selective cyanide sensing in water via fluorescence change and its application to in vivo imaging

Chem Commun (Camb). 2009 May 28:(20):2866-8. doi: 10.1039/b901140d. Epub 2009 Mar 30.

Abstract

Among the various anions, only cyanide induced the revival of fluoresecence of -Cu(2+) resulting in "Off-On" type sensing of cyanide, which can be monitored at pH 7.4 in 100% aqueous system, and has been applied to a microfluidic platform, in which fluorescent sensor -Cu(2+) displayed green fluorescence upon the addition of cyanide, the in vivo imaging of cyanide using Caenorhabditis elegans.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anions / chemistry
  • Biosensing Techniques*
  • Caenorhabditis elegans*
  • Copper / chemistry*
  • Cyanides / analysis*
  • Cyanides / chemistry
  • Fluorescent Dyes
  • Microfluidic Analytical Techniques / methods*
  • Water / analysis*
  • Water Pollutants, Chemical / analysis*
  • Water Pollutants, Chemical / chemistry

Substances

  • Anions
  • Cyanides
  • Fluorescent Dyes
  • Water Pollutants, Chemical
  • Water
  • Copper