Synaptic plasticity in the spinal dorsal horn

Hiroshi Ikeda; Takaki Kiritoshi; Kazuyuki Murase

doi:10.1016/j.neures.2009.03.004

Synaptic plasticity in the spinal dorsal horn

Neurosci Res. 2009 Jun;64(2):133-6. doi: 10.1016/j.neures.2009.03.004. Epub 2009 Mar 20.

Authors

Hiroshi Ikeda¹, Takaki Kiritoshi, Kazuyuki Murase

Affiliation

¹ Department of Human and Artificial Intelligence Systems, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan. ikeda@synapse.his.fukui-u.ac.jp

PMID: 19428692
DOI: 10.1016/j.neures.2009.03.004

Abstract

Long-term potentiation (LTP) at synapses in the spinal dorsal horn is thought to be a cellular mechanism for abnormal pain sensitivity. In this article, we review LTP in spinal projection neurons and presynaptic mechanisms of LTP in the spinal dorsal horn revealed by patch-clamp recording and optical imaging with voltage-sensitive dye.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Fluorescent Dyes
Fluorometry
Long-Term Potentiation*
Optical Phenomena
Patch-Clamp Techniques
Posterior Horn Cells / physiology*
Synapses / physiology*

Substances

Fluorescent Dyes