Abstract
Bisphosphonate holiday has been suggested as a treatment modality for oral bisphosphonate-related osteonecrosis; however, there is debate that it can undermine beneficial effects of bisphosphonate therapy. A case successfully treated after bisphosphonate holiday is presented.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Aged
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Alendronate / administration & dosage*
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Alendronate / adverse effects
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Bone Density Conservation Agents / administration & dosage*
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Bone Density Conservation Agents / adverse effects
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Collagen Type I / blood
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Drug Administration Schedule
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Female
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Humans
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Mandibular Diseases / blood
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Mandibular Diseases / chemically induced
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Mandibular Diseases / therapy*
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Osteonecrosis / blood
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Osteonecrosis / chemically induced
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Osteonecrosis / therapy*
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Osteoporosis, Postmenopausal / drug therapy
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Peptides / blood
Substances
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Bone Density Conservation Agents
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Collagen Type I
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Peptides
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collagen type I trimeric cross-linked peptide
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Alendronate