Thoracic rib solitary eosinophilic granuloma in a child

J Pediatr Orthop B. 2009 May;18(3):148-50. doi: 10.1097/bpb.0b013e32832a18f7.

Abstract

Eosinophilic granuloma is characterized by single or multiple skeletal lesions occurring predominantly in children, adolescents, and young adults, it accounts for 70% of Langerhans cell histiocytosis. The common sites are the skull, mandible, ribs, spines, and long bones particularly the femur and the humerus. Thoracic rib involvement is rarely seen. It was often regarded as malignant soft tissue tumor. We report an unusual case of eosinophilic granuloma in a female child presented with a solitary lesion at the thoracic rib.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / surgery
  • Chemotherapy, Adjuvant
  • Child
  • Cyclophosphamide / administration & dosage
  • Eosinophilic Granuloma / drug therapy
  • Eosinophilic Granuloma / pathology*
  • Eosinophilic Granuloma / surgery
  • Female
  • Humans
  • Prednisolone / administration & dosage
  • Ribs / pathology*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vincristine / administration & dosage

Substances

  • Vincristine
  • Cyclophosphamide
  • Prednisolone