Bariatric surgery among kidney transplant candidates and recipients: analysis of the United States renal data system and literature review

Transplantation. 2009 Apr 27;87(8):1167-73. doi: 10.1097/TP.0b013e31819e3f14.

Abstract

Background: Limited data exist on the safety and efficacy of bariatric surgery (BS) in patients with kidney failure.

Methods: We examined Medicare billing claims within USRDS registry data (1991-2004) to identify BS cases among renal allograft candidates and recipients.

Results: Of 188 BS cases, 72 were performed pre-listing, 29 on the waitlist, and 87 post-transplant. Roux-en-Y gastric bypass was the most common procedure. Thirty-day mortality after BS performed on the waitlist and post-transplant was 3.5%, and one transplant recipient lost their graft within 30 days after BS. BMI data were available for a subset and suggested median excess body weight loss of 31%-61%. Comparison to published clinical trials of BS in populations without kidney disease indicates comparable weight loss but higher post-BS mortality in the USRDS sample.

Conclusions: Given the substantial contributions of obesity to excess morbidity and mortality, BS warrants prospective study as a strategy for improving outcomes before and after kidney transplantation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Bariatric Surgery / mortality
  • Bariatric Surgery / statistics & numerical data*
  • Body Mass Index
  • Female
  • Gastric Bypass / methods
  • Gastroplasty / methods
  • Humans
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / statistics & numerical data*
  • Male
  • Middle Aged
  • Morbidity
  • Obesity, Morbid / complications*
  • Obesity, Morbid / surgery*
  • Postoperative Complications / epidemiology
  • Registries
  • Safety
  • Survival Rate
  • Survivors
  • United States
  • Weight Loss