Chemical characterization of the lipophilic fraction of Livistona decipiens and Livistona chinensis fruit pulps (Palmae) and assessment of their anti-hyperlipidemic and anti-ulcer activities

Nat Prod Commun. 2009 Feb;4(2):265-70.

Abstract

The oil of the dried pulps of Livistona decipiens and L. chinensis palm fruits have been studied for the first time by gas chromatography-mass spectrometry for their unsaponifiable matter (USM) and fatty acid composition (FAME). The antihyperlipidemic and anti-ulcer activities for both oils were also assayed. The principal fatty acid of L. decipiens pulp oil was oleic acid (53.4 %) and of L. chinensis pulp oil palmitic acid (47.4 %). In relation to anti-hyperlipidemic properties, the pulp oil of L. decipiens presented a better profile than that of L. chinensis, in comparison with the reference standard (simvastatin). In addition, both pulp oils showed high anti-ulcer activity using an indomethacin-induced ulceration technique in rat stomach. The relationship between the anti-hyperlipidemic, anti-ulcer and chemical composition of the pulp oils is also discussed.

MeSH terms

  • Animals
  • Anti-Ulcer Agents / chemistry*
  • Anti-Ulcer Agents / pharmacology
  • Arecaceae / chemistry*
  • Dietary Fats
  • Fruit / chemistry*
  • Hyperlipidemias / drug therapy
  • Hypolipidemic Agents / chemistry
  • Hypolipidemic Agents / pharmacology*
  • Indomethacin / toxicity
  • Lipids / blood
  • Male
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology*
  • Rats
  • Stomach Ulcer / chemically induced
  • Stomach Ulcer / drug therapy

Substances

  • Anti-Ulcer Agents
  • Dietary Fats
  • Hypolipidemic Agents
  • Lipids
  • Plant Extracts
  • Indomethacin