First report of Tsukamurella keratitis: association between T. tyrosinosolvens and T. pulmonis and ophthalmologic infections

Patrick C Y Woo; Angie H C Fong; Antonio H Y Ngan; Dorothy M W Tam; Jade L L Teng; Susanna K P Lau; Kwok-Yung Yuen

doi:10.1128/JCM.00424-09

First report of Tsukamurella keratitis: association between T. tyrosinosolvens and T. pulmonis and ophthalmologic infections

J Clin Microbiol. 2009 Jun;47(6):1953-6. doi: 10.1128/JCM.00424-09. Epub 2009 Apr 15.

Authors

Patrick C Y Woo¹, Angie H C Fong, Antonio H Y Ngan, Dorothy M W Tam, Jade L L Teng, Susanna K P Lau, Kwok-Yung Yuen

Affiliation

¹ State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology, and Department of Microbiology, the University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong. pcywoo@hkucc.hku.hk

Abstract

We describe the first two cases of Tsukamurella keratitis, presented as eye pain with or without blurring of vision. One case was associated with trichiasis and the other with contact lens wear. The two isolates were identified as T. tyrosinosolvens and T. pulmonis, respectively, by phenotypic characterization and 16S rRNA sequencing.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Actinomycetales / isolation & purification*
Actinomycetales Infections / diagnosis*
Actinomycetales Infections / microbiology
Adult
Aged, 80 and over
Bacterial Typing Techniques
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
Female
Humans
Keratitis / microbiology*
Male
Molecular Sequence Data
Phylogeny
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA

Substances

DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S

Associated data

GENBANK/FJ755300
GENBANK/FJ755301