Highly water-soluble monoboronic acid probes that show optical sensitivity to glucose based on 4-sulfo-1,8-naphthalic anhydride

J Org Chem. 2009 May 1;74(9):3544-6. doi: 10.1021/jo9002008.

Abstract

Two highly water-soluble monoboronic acid probes that display the more desirable off-on fluorescence response were synthesized based on 4-sulfo-1,8-naphthalic anhydride and a remarkable sensitivity for glucose rather than fructose and galactose was also observed.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Boronic Acids / chemical synthesis
  • Boronic Acids / chemistry*
  • Glucose / analysis*
  • Naphthalenes / analysis*
  • Naphthalimides / chemistry
  • Sensitivity and Specificity
  • Solubility
  • Water / chemistry*

Substances

  • 4-sulfo-1,8-naphthalic anhydride
  • Boronic Acids
  • Naphthalenes
  • Naphthalimides
  • Water
  • Glucose