Psychologic factors and risk of mortality after spinal cord injury

Arch Phys Med Rehabil. 2009 Apr;90(4):628-33. doi: 10.1016/j.apmr.2008.10.014.

Abstract

Objective: To identify the association of 2 distinct psychologic constructs, personality and purpose in life (PIL), with risk of early mortality among persons with spinal cord injury (SCI).

Design: Prospective cohort study with health data collected in late 1997 and early 1998 and mortality status ascertained in December 2005.

Setting: A large rehabilitation hospital in the southeastern United States.

Participants: Adults (N=1386) with traumatic SCI, at least 1 year postinjury.

Interventions: Not applicable.

Main outcome measures: We first evaluated the significance of a single psychologic predictor (a total of 6 scales) while controlling for biographic and injury predictors using Cox proportional hazards modeling and subsequently built a comprehensive model based on an optimal group of psychologic variables.

Results: There were a total of 224 (16.2%) observed deaths in the full sample. The total number of deaths was reduced to 164 in the final statistical model (of 1128 participants) because of missing data. All 6 psychologic factors were statistically significant in the model that was adjusted for biographic and injury factors, whereas only 3 psychologic factors were retained in the final comprehensive model, including 2 personality scales (Impulsive Sensation Seeking, Neuroticism-Anxiety) and the PIL scale. The final comprehensive model only modestly improved the overall prediction of survival compared with the model with only biographic and injury variables, because the pseudo-R(2) increased from 0.121 to 0.129, and the concordance increased from 0.730 to 0.747.

Conclusions: The results affirm the importance of psychologic factors in relation to survival after SCI.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Cohort Studies
  • Comorbidity
  • Confidence Intervals
  • Female
  • Humans
  • Male
  • Models, Statistical
  • Personality / classification*
  • Personality Disorders / epidemiology
  • Prospective Studies
  • Risk Factors
  • Southeastern United States / epidemiology
  • Spinal Cord Injuries / mortality*
  • Spinal Cord Injuries / psychology*
  • Spinal Cord Injuries / rehabilitation
  • Survival Rate