Factors associated with maternal death in women admitted to an intensive care unit with severe maternal morbidity

Int J Gynaecol Obstet. 2009 Jun;105(3):252-6. doi: 10.1016/j.ijgo.2009.01.025. Epub 2009 Apr 1.

Abstract

Objective: To identify factors associated with maternal death among women with severe maternal morbidity.

Methods: A retrospective study of 673 women admitted to an obstetric intensive care unit was undertaken. The odds ratios (OR) and 95% confidence intervals (95% CI) were calculated for selected characteristics. The maternal mortality and severe maternal morbidity ratios were determined for groups of complications according to outcome (death or survival).

Results: The risk of maternal death was higher among adolescents (OR 3.3; 95% CI, 1-9.7) and patients referred from other hospitals (OR 9.8; 95% CI, 2.7-53.3). The severe maternal morbidity ratio was 46.6 per 1000 deliveries and the mortality:morbidity ratio 1:37.4. Obstetric complications led to 65.8% of admissions and 50% of maternal deaths. The number of interventions/procedures and total maximum sequential organ failure assessment score were higher in cases of death.

Conclusion: The strong association between interhospital transfer and maternal death suggests delays in diagnosis, management, and referral. Adopting organ dysfunction-based criteria may contribute toward identifying the most severe cases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Child
  • Cohort Studies
  • Female
  • Hospital Mortality
  • Humans
  • Intensive Care Units / statistics & numerical data
  • Maternal Mortality*
  • Middle Aged
  • Multiple Organ Failure / mortality*
  • Patient Transfer / statistics & numerical data
  • Pregnancy
  • Pregnancy Complications / mortality*
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Time Factors
  • Young Adult