Intravitreal triamcinolone acetonide injection at the time of pars plana vitrectomy for retained lens material

Korean J Ophthalmol. 2009 Mar;23(1):13-6. doi: 10.3341/kjo.2009.23.1.13. Epub 2009 Mar 9.

Abstract

Purpose: To report the experiences at our institute of pars plana vitrectomy (PPV) in combination with intravitreal triamcinolone acetonide (IVTA) injection in patients with retained lens material after cataract surgery.

Methods: The medical records of patients who underwent PPV between January 2005 and December 2006 after complicated cataract surgery in which lens material was dropped into the vitreous cavity were reviewed retrospectively.

Results: Five eyes of five patients were treated by vitrectomy and removal of the dislocated lens material and were administered an adjuvant intravitreal injection of 4 mg triamcinolone acetonide at the end of surgery. IVTA administration induced a rapid improvement in vision within six weeks postoperatively. Final visual acuity was 20/32 or better in all patients. Inflammatory cystoid macular edema (CME) that existed preoperatively was promptly improved after IVTA. Intraocular pressure increased transiently in one patient. No procedure-related complications were observed.

Conclusions: PPV with additional IVTA was successfully performed in five eyes with retained lens material and resulted in a marked resolution of vitreous inflammation, an improvement in CME and rapid visual recovery. The authors recommend that IVTA administration should be investigated more thoroughly as an adjunct during the management of retained lens material.

Keywords: Cataract; Cystoid macular edema; Dropped nucleus; Retained lens material; Triamcinolone acetonide.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cataract Extraction / adverse effects
  • Device Removal / methods*
  • Female
  • Follow-Up Studies
  • Glucocorticoids / administration & dosage*
  • Humans
  • Injections
  • Intraoperative Care / methods
  • Lens Subluxation / pathology
  • Lens Subluxation / surgery*
  • Lenses, Intraocular / adverse effects*
  • Macular Edema / etiology
  • Macular Edema / pathology
  • Macular Edema / surgery*
  • Male
  • Middle Aged
  • Reoperation
  • Retrospective Studies
  • Time Factors
  • Tomography, Optical Coherence
  • Treatment Outcome
  • Triamcinolone Acetonide / administration & dosage*
  • Visual Acuity
  • Vitrectomy / methods*
  • Vitreous Body

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide