Polyester-graft-phosphorylcholine prepared by ring-opening polymerization and click chemistry

Chem Commun (Camb). 2009 Feb 21:(7):815-7. doi: 10.1039/b817600k. Epub 2008 Dec 17.

Authors

Beth M Cooper¹, Delphine Chan-Seng, Debasis Samanta, Xiongfei Zhang, Sangram Parelkar, Todd Emrick

Affiliation

¹ Department of Polymer Science and Engineering, University of Massachusetts, Amherst, MA 01003, USA.

PMID: 19322451
DOI: 10.1039/b817600k

Abstract

Phosphorylcholine (PC)-substitution on aliphatic polyesters is accomplished by click chemistry with PC-substituted azides.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Cell Line, Tumor
Cell Survival / drug effects
Humans
Magnetic Resonance Spectroscopy
Phosphorylcholine / chemistry*
Polyesters / chemical synthesis
Polyesters / chemistry*
Polyesters / toxicity

Substances

Polyesters
Phosphorylcholine