Successful introduction of modern mini-invasive technologies of echinococcosis treatment necessitate problem-solving in early exposure of relapse and diagnosis verification at small cysts. It is ascertained that development rate of recurrent cyst decreases with size enlargement. Median of growth rate had amounted 1.5 mm a month (quartile--1.02 and 2.4 mm/month) till the diameter of the cyst reached 5 cm. Carrying out immune-enzyme analysis allows to forecast treatment results in terms of 3-3.5 years in most observations. Taking this data into account algorithm of early relapse diagnosis was worked out. Long-term results of surgical treatment of echinococcosis of various localization were studied in 652 patients. Regular check-up according to developed algorithm allowed to reveal relapses after 12.4 +/- 7.7 months on average, whereas in the absence of regular check up relapses were diagnosed after 27.9 +/- 15.6 months on average (p=0.0005). Revealed cysts were relatively bigger (3.8 +/- 1.1 and 8.0 +/- 3.7 cm respectively), that at regular check-up according to algorithm.