A novel approach to prepare (90)Y-EGMP patches for superficial brachytherapy

Sanjay Kumar Saxena; Ashok K Pandey; Pankaj Tandon; Rubel Chakravarty; A V R Reddy; Ashutosh Dash; Meera Venkatesh

doi:10.1016/j.apradiso.2009.02.059

A novel approach to prepare (90)Y-EGMP patches for superficial brachytherapy

Appl Radiat Isot. 2009 Jul-Aug;67(7-8):1416-20. doi: 10.1016/j.apradiso.2009.02.059. Epub 2009 Feb 23.

Authors

Sanjay Kumar Saxena¹, Ashok K Pandey, Pankaj Tandon, Rubel Chakravarty, A V R Reddy, Ashutosh Dash, Meera Venkatesh

Affiliation

¹ Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.

PMID: 19297181
DOI: 10.1016/j.apradiso.2009.02.059

Abstract

A novel method to prepare (90)Y-EGMP patches has been developed for brachytherapy applications.EGMP films of 1cmx1cm size, incorporating approximately 185MBq of (90)Y were prepared and sealed between thin plastic sheets with uniform distribution of (90)Y. The leachability of (90)Y from radioactive patches was less than 0.01%. There was no leakage of radioactivity from radioactive patches, when tested in water or saline. The studies related to establish therapeutic efficacy of these patches are warranted.

MeSH terms

Brachytherapy / methods*
Equipment and Supplies, Hospital
Materials Testing
Membranes, Artificial*
Yttrium Radioisotopes / therapeutic use*

Substances

Membranes, Artificial
Yttrium Radioisotopes