The first treatment recommendations on the diagnosis and treatment of cervical carcinoma were published by experts in the DKG's Working Group on Gynecological Oncology (Arbeitsgemeinschaft Gynäkologische Onkologie, AGO) in 1999 (S1 guideline). The purpose of the guidelines is to explicitly present current knowledge regarding specific medical care problems, evaluate them from methodological and clinical viewpoints, clarify contradictory positions, and define the current procedure of choice after weighing up advantages and disadvantages. It is therefore necessary for guidelines to have their validity continually checked and updated. Interdisciplinary collaboration is an indispensable principle for high-quality care in the field of oncology. This should be borne in mind when establishing recommendations for care. The first updating of the guideline was accordingly carried out in May 2004, with a structured consensus process being carried out by an interdisciplinary group of experts representative of the group of users (S2 guideline). The S2 guideline "Diagnosis and Treatment of Cervical Carcinoma" has now been revised again between October 2007 and January 2008 by the AGO's Uterus Commission.