Toward the synthesis of fine chemicals from lactose: preparation of D-xylo and L-lyxo-aldohexos-5-ulose derivatives

Carbohydr Res. 2009 Apr 21;344(6):717-24. doi: 10.1016/j.carres.2009.01.014. Epub 2009 Jan 19.

Abstract

The transformation of (5R)-2,6-di-O-benzyl-5-C-methoxy-beta-D-galactopyranosyl-(1-->4)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal (8) into partially protected derivatives of D-xylo- and L-lyxo-aldohexos-5-ulose has been reported, applying appropriate epimerisation methods to its 3'-O- and 4'-O-protected alcoholic derivatives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glycosides / chemical synthesis*
  • Glycosides / chemistry*
  • Lactose / analogs & derivatives*
  • Lactose / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Stereoisomerism

Substances

  • Glycosides
  • Lactose