Morbidity and functional outcomes following gastro-omental free flap reconstruction of circumferential pharyngeal defects

Head Neck. 2009 May;31(5):655-63. doi: 10.1002/hed.21016.

Abstract

Background: In patients with extensive soft tissue fibrosis requiring circumferential pharyngeal reconstruction following definitive radiotherapy and/or chemotherapy, we take advantage of abundant omental progenitor factors in the tubed gastro-omental free flap. This study reviews our experience with this flap.

Methods: Review of 11 patients (median follow-up, 2.8 years) undergoing total pharyngolaryngectomy following organ preservation protocols for recurrent squamous cell carcinoma (n = 9) and stricture (n = 2).

Results: Operative morbidity and mortality rates were 54% and 9%, respectively. One patient died following carotid rupture. Complications included: chyle leak (18%), pharyngocutaneous fistula (9%), and late stricture (27%). Ten patients (91%) achieved oral diet, and all 7 patients (100%) considered suitable for tracheoesophageal speech rehabilitation achieved functional speech. Seven patients remain alive without disease at a median of 41 months following surgery.

Conclusions: The gastro-omental flap provides a viable option in high-risk patients undergoing circumferential pharyngeal reconstruction.

MeSH terms

  • Aged
  • Carcinoma, Squamous Cell / mortality
  • Carcinoma, Squamous Cell / surgery
  • Constriction, Pathologic / surgery
  • Deglutition*
  • Female
  • Fistula / etiology
  • Fistula / surgery
  • Follow-Up Studies
  • Gastric Mucosa / blood supply
  • Gastric Mucosa / transplantation
  • Gastric Outlet Obstruction / etiology
  • Gastric Outlet Obstruction / therapy
  • Hematoma / etiology
  • Hematoma / surgery
  • Hernia, Abdominal / etiology
  • Hernia, Abdominal / surgery
  • Humans
  • Hypopharyngeal Neoplasms / mortality
  • Hypopharyngeal Neoplasms / surgery
  • Laryngeal Neoplasms / mortality
  • Laryngeal Neoplasms / surgery
  • Laryngectomy*
  • Larynx, Artificial
  • Length of Stay
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / surgery
  • Omentum / blood supply
  • Omentum / transplantation
  • Pharynx / surgery*
  • Postoperative Complications*
  • Pulmonary Embolism / drug therapy
  • Pulmonary Embolism / surgery
  • Salvage Therapy
  • Speech*
  • Surgical Flaps* / blood supply
  • Surgical Wound Dehiscence / etiology
  • Surgical Wound Dehiscence / surgery