Quasi-multistatic MIST beamforming for the early detection of breast cancer

IEEE Trans Biomed Eng. 2010 Apr;57(4):830-40. doi: 10.1109/TBME.2009.2016392. Epub 2009 Feb 27.

Abstract

Microwave imaging via space-time (MIST) beamforming has been shown to be one of the most promising imaging modalities for detecting small malignant breast tumors. This paper outlines two modifications to the MIST system developed by Hagness for the early detection of breast cancer, resulting in a quasi-multistatic MIST beamformer (multi-MIST). Multistatic MIST beamforming involves illuminating the breast with an ultrawideband (UWB) signal from one antenna while collecting the reflections at an array of antennas, as opposed to traditional monostatic MIST beamforming where only the transmitting antenna records the reflections from the breast. In order to process the multistatic data, traditional data-adaptive artifact removal algorithms have to be modified to accommodate signals from all antennas. Also, the MIST beamforming algorithm, which spatially focuses the signal and compensates for frequency-dependent propagation effects, has to be modified. The algorithms are tested on a 2-D anatomically accurate finite-difference time-domain model of the breast. The multi-MIST beamformer described here is shown to offer an improved signal to clutter ratio when compared to the traditional monostatic MIST beamformer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Artifacts
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / pathology*
  • Computer Simulation
  • Diagnostic Imaging / methods*
  • Early Detection of Cancer / methods*
  • Female
  • Humans
  • Microwaves*
  • Models, Biological
  • Signal Processing, Computer-Assisted*