Russujaponols G-L, illudoid sesquiterpenes, and their neurite outgrowth promoting activity from the fruit body of Russula japonica

Chem Pharm Bull (Tokyo). 2009 Mar;57(3):311-4. doi: 10.1248/cpb.57.311.

Abstract

Six new illudoid sesquiterpene, russujaponols G-L (1-6) were isolated from the fruit bodies of Russula japonica. Their structures were established primarily by 2D NMR experiments. Furthermore, russujaponols I-K showed neurite outgrowth promoting activity in the primary cultured rat cortical neurons.

MeSH terms

  • Animals
  • Basidiomycota / chemistry*
  • Cells, Cultured
  • Fruit / chemistry*
  • Neurites / drug effects*
  • Rats
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / isolation & purification
  • Sesquiterpenes / pharmacology

Substances

  • Sesquiterpenes