Glucocorticoids, 11beta-hydroxysteroid dehydrogenase: mother, fetus, or both?

Endocrinology. 2009 Mar;150(3):1073-4. doi: 10.1210/en.2008-1577.

Authors

John R G Challis¹, Kristin Connor

Affiliation

¹ Department of Physiology, University of Toronto, Toronto, Ontario, Canada. j.challis@msfhr.org

PMID: 19240262
DOI: 10.1210/en.2008-1577

No abstract available

Publication types

Comment

MeSH terms

11-beta-Hydroxysteroid Dehydrogenase Type 2 / genetics
11-beta-Hydroxysteroid Dehydrogenase Type 2 / metabolism
11-beta-Hydroxysteroid Dehydrogenase Type 2 / physiology
11-beta-Hydroxysteroid Dehydrogenases / genetics
11-beta-Hydroxysteroid Dehydrogenases / metabolism
11-beta-Hydroxysteroid Dehydrogenases / physiology*
Animals
Female
Fetus / enzymology
Fetus / metabolism*
Gene Expression Regulation, Enzymologic / drug effects
Glucocorticoids / metabolism*
Glucocorticoids / pharmacology
Humans
Maternal-Fetal Exchange / drug effects
Maternal-Fetal Exchange / physiology*
Mice
Mice, Knockout
Mothers*
Placenta / metabolism
Pregnancy

Substances

Glucocorticoids
11-beta-Hydroxysteroid Dehydrogenase Type 2
11-beta-Hydroxysteroid Dehydrogenases
HSD11B2 protein, human