Extended-spectrum beta-lactamase-producing Enterobacteriaceae in a Malian orphanage

Emerg Infect Dis. 2009 Mar;15(3):472-4. doi: 10.3201/eid1503.071637.

Abstract

We show high rates of extended-spectrum beta-lactamase-producing Enterobacteriaceae carriage among the staff and children at an orphanage in Bamako, Mali. Enterobacteriaceae colonized in 100% and 63%, respectively, of the 38 children and 30 adults studied. Use of antimicrobial drugs appeared excessive and inappropriate; decontamination and hygiene protocols were also questioned.

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Caregivers / statistics & numerical data
  • Carrier State / epidemiology
  • Carrier State / microbiology
  • Child
  • Child, Orphaned / statistics & numerical data
  • Cross-Sectional Studies
  • Disease Outbreaks*
  • Drug Resistance, Multiple, Bacterial
  • Enterobacteriaceae / classification
  • Enterobacteriaceae / drug effects
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / diagnosis
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology
  • Humans
  • Infant
  • Mali / epidemiology
  • Orphanages*
  • beta-Lactamases / biosynthesis*

Substances

  • Anti-Bacterial Agents
  • beta-Lactamases