Effects of artificial colloids on haemostasis

Br J Hosp Med (Lond). 2009 Feb;70(2):101-3. doi: 10.12968/hmed.2009.70.2.38909.

Abstract

Artificial colloids are used in situations with a high risk of bleeding such as trauma or during surgery. Although more efficacious than crystalloids, colloids can be associated with derangements of the haemostatic system and may also interfere with normal haemostasis via a number of different mechanisms.

Publication types

  • Review

MeSH terms

  • Blood Coagulation / drug effects
  • Gelatin / pharmacology*
  • Gelatin / therapeutic use
  • Hemodynamics / drug effects
  • Hemostasis / drug effects*
  • Humans
  • Hydroxyethyl Starch Derivatives / pharmacology*
  • Hydroxyethyl Starch Derivatives / therapeutic use
  • Plasma Substitutes / pharmacology*
  • Plasma Substitutes / therapeutic use
  • Platelet Aggregation / drug effects

Substances

  • Hydroxyethyl Starch Derivatives
  • Plasma Substitutes
  • Gelatin