Emergence of plasmid-mediated quinolone resistance among non-Typhi Salmonella enterica isolates from humans in the United States

Antimicrob Agents Chemother. 2009 May;53(5):2142-4. doi: 10.1128/AAC.01288-08. Epub 2009 Feb 17.

Abstract

Plasmid-mediated quinolone resistance determinants are emerging among gram-negative pathogens. Here we report results of a retrospective study investigating the prevalence of aac(6')-Ib-cr, qepA, and qnr genes among 19,010 human isolates of non-Typhi Salmonella enterica collected in the United States from 1996 to 2006.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acetyltransferases / genetics
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics
  • DNA Gyrase / genetics
  • Drug Resistance, Bacterial / genetics*
  • Humans
  • Microbial Sensitivity Tests
  • Plasmids / genetics*
  • Prevalence
  • Quinolones / pharmacology*
  • Salmonella Infections / epidemiology*
  • Salmonella Infections / microbiology
  • Salmonella enterica / classification
  • Salmonella enterica / drug effects*
  • Salmonella enterica / genetics
  • Salmonella enterica / isolation & purification
  • Serotyping
  • United States / epidemiology

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Quinolones
  • Acetyltransferases
  • DNA Gyrase