Sensitivity of the classification of psoriatic arthritis criteria in early psoriatic arthritis

J Rheumatol. 2009 Feb;36(2):368-70. doi: 10.3899/jrheum.080596. Epub 2009 Feb 4.

Abstract

Objective: To determine the sensitivity of the CASPAR criteria in patients with early psoriatic arthritis (PsA).

Methods: Consecutive patients with a clinical diagnosis of PsA and a disease duration < 12 months were enrolled for study. The proportion of patients meeting the criteria (i.e., the sensitivity) was determined.

Results: Forty-four patients with early PsA (23 women, 21 men; mean age 51 yrs, range 16-90) were enrolled. Mean disease duration (+/- SD) was 15.8 +/- 14.3 weeks (range 0.1-50.9 wks). Thirty-four patients satisfied the criteria at the first visit (sensitivity 77.3%). Most patients met the skin and laboratory criterion, i.e., they were rheumatoid factor-negative, while only 2 satisfied the radiologic criterion.

Conclusion: Our findings suggest a less satisfactory performance of the CASPAR criteria when applied in early PsA. Lower sensitivity could mainly depend on the small proportion of patients fulfilling the radiologic criterion.

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Arthritis, Psoriatic / classification*
  • Arthritis, Psoriatic / diagnosis*
  • Arthritis, Psoriatic / physiopathology
  • Arthrography / methods
  • Arthrography / standards*
  • Clinical Laboratory Techniques / methods
  • Diagnosis, Differential
  • Disease Progression
  • Early Diagnosis
  • Female
  • Humans
  • Joints / pathology*
  • Joints / physiopathology
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Rheumatoid Factor / analysis
  • Rheumatoid Factor / metabolism
  • Severity of Illness Index
  • Skin / immunology
  • Skin / pathology
  • Skin / physiopathology

Substances

  • Rheumatoid Factor