Molecular mechanisms of drug resistance

Int J Clin Pharmacol Ther. 2009 Jan;47(1):49-50. doi: 10.5414/cpp47049.
No abstract available

MeSH terms

  • Antimetabolites, Antineoplastic / metabolism
  • Antimetabolites, Antineoplastic / pharmacology
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Apoptosis / drug effects
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / genetics
  • Breast Neoplasms / metabolism*
  • Breast Neoplasms / pathology
  • Cell Adhesion / drug effects
  • Cell Line, Tumor
  • Colonic Neoplasms / genetics
  • Colonic Neoplasms / pathology
  • DNA Repair
  • DNA Replication
  • Dose-Response Relationship, Drug
  • Drug Resistance, Neoplasm*
  • Epigenesis, Genetic
  • Female
  • Fluorouracil / metabolism
  • Fluorouracil / pharmacology
  • Fluorouracil / therapeutic use*
  • Gene Expression
  • Genes, p53 / genetics
  • Humans
  • Methylation
  • Mitosis
  • Receptor, ErbB-2 / genetics
  • Signal Transduction / drug effects
  • Uracil-DNA Glycosidase

Substances

  • Antimetabolites, Antineoplastic
  • Receptor, ErbB-2
  • Uracil-DNA Glycosidase
  • Fluorouracil