N-terminal pro-BNP plasma levels before and after percutaneous transvenous mitral commissurotomy for mitral stenosis

Davinder S Chadha; Ganesan Karthikeyan; Kashish Goel; Sushil K Malani; Sandeep Seth; Sandeep Singh; Anil Dhall; Balram Bhargava

doi:10.1016/j.ijcard.2009.01.001

N-terminal pro-BNP plasma levels before and after percutaneous transvenous mitral commissurotomy for mitral stenosis

Int J Cardiol. 2010 Oct 8;144(2):238-40. doi: 10.1016/j.ijcard.2009.01.001. Epub 2009 Feb 4.

Authors

Davinder S Chadha, Ganesan Karthikeyan, Kashish Goel, Sushil K Malani, Sandeep Seth, Sandeep Singh, Anil Dhall, Balram Bhargava

PMID: 19195726
DOI: 10.1016/j.ijcard.2009.01.001

Abstract

In this study, we investigated the change in N-terminal pro-brain natriuretic peptide (NT-pro-BNP) plasma levels among 44 consecutive patients with mitral stenosis, 10 min before and 24 h after undergoing percutaneous transvenous mitral commissurotomy (PTMC). The procedure was successful in all patients and a significant decline was noted in NT-pro-BNP levels. Reduction of NT-pro-BNP was more marked in patients in sinus rhythm as compared to those with atrial fibrillation. In conclusion, serial measurement of plasma NT-pro-BNP levels might be a useful noninvasive method for documenting the success of PTMC among patients in sinus rhythm.

Publication types

Letter

MeSH terms

Adult
Cardiac Surgical Procedures / methods
Female
Humans
Male
Mitral Valve / surgery*
Mitral Valve Stenosis / blood*
Mitral Valve Stenosis / surgery*
Natriuretic Peptide, Brain / blood*
Peptide Fragments / blood*

Substances

Peptide Fragments
pro-brain natriuretic peptide (1-76)
Natriuretic Peptide, Brain