Infection with hepatitis C virus among HIV-infected pregnant women in Thailand

Infect Dis Obstet Gynecol. 2008:2008:840948. doi: 10.1155/2008/840948. Epub 2009 Jan 27.

Abstract

Objective: The purpose of this study was to describe the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among a cohort of pregnant Thai women.

Methods: Samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies in Bangkok, Thailand, were tested for HCV.

Results: Among HIV-infected pregnant women, HCV seroprevelance was 3.8% and the active HCV infection rate was 3.0%. Among HIV-uninfected pregnant women, 0.3% were HCV-infected. Intravenous drug use by the woman was the factor most strongly associated with HCV seropositivity. Among 48 infants tested for HCV who were born to HIV/HCV coinfected women, two infants were HCV infected for an HCV transmission rate of 4.2% (95% 0.51-14.25%).

Conclusions: HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Comorbidity
  • Female
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • Hepatitis C / epidemiology*
  • Hepatitis C / transmission
  • Hepatitis C Antibodies / blood*
  • Humans
  • Infectious Disease Transmission, Vertical* / prevention & control
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Seroepidemiologic Studies
  • Thailand
  • Young Adult

Substances

  • Hepatitis C Antibodies