Synthesis of sphere nanostructured MoS(2) is reported. Characterization of the synthesized MoS(2) was investigated by X-ray diffraction, nitrogen adsorption, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). It was found that the obtained MoS(2) is composed of layers that bend to form mostly spheres, with an average diameter of approximately 180 nm. The growth in crystallinity is mainly due to the increased number of the round-stacked layers of MoS(2). The catalytic activity and selectivity of the synthesized nanostructured MoS(2) for the dibenzothiophene hydrodesulfurization were investigated. The closed-circle MoS(2) layers exhibited a high selectivity for the direct sulfur removal.