A new flavonol galloylrhamnoside and a new lignan glucoside from the leaves of Koelreuteria henryi Dummer

J Nat Med. 2009 Apr;63(2):209-14. doi: 10.1007/s11418-009-0314-z. Epub 2009 Jan 30.

Abstract

A new flavonol galloylrhamnoside, kaempferol 3-O-(2'',3''-di-O-galloyl)-alpha-L: -rhamnopyranoside, and a new lignan glycoside, hinokinin 7-O-beta-D: -glucopyranoside were isolated from the leaves of Koelreuteria henryi, along with 18 known compounds, including six flavonol glycosides (3-8), three lignans (9-11), four chlorophyll derivatives (12-15), two steroids (16, 17), and three aromatic compounds (18-20). The structures were determined on the basis of spectral analysis and chemical evidence. The scavenging effect of 1-8 and 20 on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Compounds 1, 5, 6, and 20 showed more potent activity than that of trolox.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Biphenyl Compounds
  • Chromans / pharmacology
  • Dioxoles / isolation & purification
  • Dioxoles / pharmacology
  • Flavonols / isolation & purification*
  • Flavonols / pharmacology
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology*
  • Glucosides / isolation & purification
  • Glucosides / pharmacology
  • Glycosides / isolation & purification
  • Glycosides / pharmacology
  • Kaempferols / isolation & purification
  • Kaempferols / pharmacology
  • Lignans / isolation & purification
  • Lignans / pharmacology
  • Medicine, Chinese Traditional
  • Picrates
  • Plant Leaves
  • Proanthocyanidins / isolation & purification
  • Proanthocyanidins / pharmacology
  • Sapindaceae / chemistry*
  • Spectrum Analysis
  • Taiwan

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Chromans
  • Dioxoles
  • Flavonols
  • Free Radical Scavengers
  • Glucosides
  • Glycosides
  • Kaempferols
  • Lignans
  • Picrates
  • Proanthocyanidins
  • hinokinin 7-O-beta-D-glucopyranoside
  • kaempferol 3-O-(2''3''di-O-galloyl)-alpha-L-rhamnopyranoside
  • 1,1-diphenyl-2-picrylhydrazyl
  • 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid