Abstract
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis with the potential of human-to-human transmission that affects wide areas in Asia, Southeastern Europe, and Africa. Hemorrhagic manifestations constitute a prominent symptom of late stage disease with case fatality rates from 3 to 50%. We present a case of CCHF complicated by hemorrhagic pleural effusion and resulting in resolution without chest tube drainage in a 9-year-old boy. The diagnosis of CCHF was confirmed by enzyme-linked immunosorbent assay tests. Both serum and pleural fluid CCHF IgM were positive at titers of 1/1,600 and 1/6,400, respectively.
MeSH terms
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Animals
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Antiviral Agents / administration & dosage
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Antiviral Agents / therapeutic use*
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Child
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Enzyme-Linked Immunosorbent Assay
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Hemorrhagic Fever Virus, Crimean-Congo / immunology
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Hemorrhagic Fever Virus, Crimean-Congo / isolation & purification*
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Hemorrhagic Fever, Crimean / complications*
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Hemorrhagic Fever, Crimean / diagnosis
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Hemorrhagic Fever, Crimean / drug therapy
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Humans
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Immunoglobulin M / analysis
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Male
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Pleural Effusion / diagnostic imaging
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Pleural Effusion / drug therapy
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Pleural Effusion / virology*
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Radiography
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Ribavirin / administration & dosage
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Ribavirin / therapeutic use*
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Ticks / virology
Substances
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Antiviral Agents
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Immunoglobulin M
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Ribavirin